Organic nitroso compounds
Medchemexpress LLC 4-nitroso hydrochlorothiazide-13C,15N2,d2 | 63779-86-2 | 99.3% | C613CH5D2ClN215N2O5S2 | 100 UG
4-Nitroso hydrochlorothiazide-13C,15N2,d2 is an isotopically labeled compound, primarily used for research purposes. This compound serves as a tracer and an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. The incorporation of stable heavy isotopes like deuterium, 13C, and 15N into drug molecules is a common practice in drug development to facilitate quantitation and to study their pharmacokinetic and metabolic profiles, as deuteration can influence these aspects.
- Used as a tracer in research applications
- Functions as an internal standard for quantitative analysis
- Suitable for use with NMR, GC-MS, or LC-MS techniques
- Incorporates stable heavy isotopes for enhanced research capabilities
Medchemexpress LLC N-Nitroso-N-methylurea | 684-93-5 | 99.7% | 103.08 | 2 G
N-Nitroso-N-methylurea is a potent carcinogen, mutagen, and teratogen. It acts as a direct-acting alkylating agent that interacts with DNA, targeting multiple animal organs to cause various cancers and/or degenerative diseases. It is also a precursor in the synthesis of diazomethane.
- Potent carcinogen, mutagen, and teratogen
- Direct-acting alkylating agent that interacts with DNA
- Targets multiple animal organs to cause various cancers and/or degenerative diseases
- Precursor in the synthesis of diazomethane
- For research use only
Cayman Chemical N-NItroso SarcosIn 250mg
A carcinogen; induces the formation of metastatic liver carcinomas in mice at 225 mg/kg
Cayman Chemical 5-NItroso-8-quInolInol 50mg
An HDAC inhibitor, antitumor agent that at 10 μM can induce oxidative stress contributing to apoptosis and differentiation in MCF-7 breast cancer cells; inhibits T. gondii tachyzoite propagation in human fibroblasts (EC50 = 80 nM) and inhibits P. falciparum growth in human red blood cells (EC50 = 1.3 μM)
World Precision Instrument SNAP S-Nitroso-N-acetyl-D-penicillamine-SNAP25
SNAP is a stable green crystalline S-nitrosothiol compound that mimics the action of nitric oxide in vivo. It has vasodilatory properties and has been shown to relax isolated bovine coronary artery rings by activating soluble granulate cyclase. This reagent also actuates apoptosis in mouse thymocytes and has been accounted for reversible inactivation of protein Kinase C. SNAP can be used for calibration of all WPI NO sensors. Call for details. M.W. 220.2, Purity > 98% by NMR or TLC.
Cayman Chemical N-NItroso SarcosIn-d3 1mg
An internal standard for the quantification of nitroso sarcosine by GC- or LC-MS
Cayman Chemical N-NItroso-N-methylnIlIn 100mg
An N-nitrosamine; induces the formation of esophageal, pharyngeal, and tongue tumors in rats at 200 mg/L in the drinking water or 15 mg/ml via oral gavage; toxic to rats (LD50s = 336 and 225 mg/kg for male and female rats, respectively); reduces survival of hamsters but only induces a low incidence of tumors at 5 mg/week for a total dose of 1.8 mmol
Medchemexpress LLC N-Nitroso-N-methylurea | 684-93-5 | 103.08 | 5 G
N-Nitroso-N-methylurea is a potent carcinogen, mutagen, and teratogen. It functions as a direct-acting alkylating agent, interacting with DNA, and is known to target multiple animal organs, potentially leading to various cancers or degenerative diseases. This compound also serves as a precursor in the synthesis of diazomethane. It is a flammable solid intended for laboratory use in the manufacture of substances and is stable under recommended storage conditions.
- Functions as a direct-acting alkylating agent
- Interacts with DNA
- Targets multiple animal organs
- Leads to various cancers and/or degenerative diseases
- Precursor in the synthesis of diazomethane
- Used in animal modeling to construct tumor models
Medchemexpress LLC N-Nitroso-3-azabicyclo[3.3.0]octane-d4 | 1346604-35-0 | 95.0% | C7H8D4N2O | 100 MG
N-Nitroso-3-azabicyclo[3.3.0]octane-d4 is the deuterium labeled N-Nitroso-3-azabicyclo[3.3.0]octane. It is for research use only and not intended for human use. Deuterium labeled compounds can be used as tracers or internal standards for quantitative analysis by methods like NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC S-nitroso-N-acetyl-DL-penicillamine | 67776-06-1 | 98.8% | 100 MG
S-nitroso-N-acetyl-DL-penicillamine (SNAP) is a nitric oxide donor used in biochemical and physiological research to release NO. It acts as a stable inhibitor of platelet aggregation and is supplied as a powdered reagent for laboratory studies.
- Acts as a nitric oxide donor and inhibitor of platelet aggregation.
- Molecular formula C7H12N2O4S and molecular weight 220.25 g/mol.
- Purity 98.8% (as supplied).
- Powder form, commonly available in small research pack sizes such as 100 MG.
- Stored at low temperature to maintain stability (powder storage at -20°C recommended).
- Used in studies of nitric oxide signaling, platelet function, and related assays.
Medchemexpress LLC 4-nitroso hydrochlorothiazide-13C,15N2,d2 | 63779-86-2 | 99.3% | C613CH5D2ClN215N2O5S2 | 1 MG
4-Nitroso hydrochlorothiazide-13C,15N2,d2 is a deuterium, 13C-, and 15-labeled version of 4-Nitroso hydrochlorothiazide. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules primarily for use as tracers in the drug development process for quantitation. Deuteration is notable for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- This compound serves as a tracer.
- It can be utilized as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC Butanoic acid, 4-(methylnitrosoamino)- | 61445-55-4 | MFCD00869939 | 99.9% | 146.14 g/mol | C5H10N2O3 | 25 MG
N-Nitroso-N-methyl-4-aminobutyric acid is a tobacco-specific nitrosamine used as a research chemical and reference standard for analytical and toxicology studies. The product is supplied as a high-purity, neat chemical with documented analytical data and handling guidance.
Medchemexpress LLC BUSPIRONE 50.0MG
Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent and can be used for the generalized anxiety disorder research.
World Precision Instrument SNAP S-Nitroso-N-acetyl-D-penicillamine-SNAP50
SNAP is a stable green crystalline S-nitrosothiol compound that mimics the action of nitric oxide in vivo. It has vasodilatory properties and has been shown to relax isolated bovine coronary artery rings by activating soluble granulate cyclase. This reagent also actuates apoptosis in mouse thymocytes and has been accounted for reversible inactivation of protein Kinase C. SNAP can be used for calibration of all WPI NO sensors. Call for details. M.W. 220.2, Purity > 98% by NMR or TLC.